Dobixime 200mg (en)

Uncomplicated/uncomplicated urinary tract infections, nephritis-pyelonephritis, otitis media, pharyngitis and tonsils, acute/chronic bronchitis, uncomplicated gonorrhea, typhoid, dysentery.

Ingredient

Cefixim.

Indications

Uncomplicated/uncomplicated urinary tract infections, nephritis-pyelonephritis, otitis media, pharyngitis and tonsils, acute/chronic bronchitis, uncomplicated gonorrhea, typhoid, dysentery.

Mild – moderate community-acquired pneumonia.

Dosage

Adults, children > 12 years old (> 50kg) 200 mg twice daily or 400 mg daily.

Children 6 months-12 years: 8 mg/kg/day 1 time or 2 divided doses.

Adults with renal impairment: CrCl 21-60mL/min: 300 mg/day, CrCl < 20mL/min: 200 mg/day

Usage

Should be taken on an empty stomach: Dissolve the tablet in a glass of water, drink before eating.

Contraindications

Hypersensitivity to any component of the drug/cephalosporin group.

History of penicillin-induced anaphylaxis.

Cautious

History of penicillin allergy and other cephalosporins.

History of gastrointestinal diseases, colitis.

Pregnant/lactating women; babies < 6 months old.

Avoid prolonged administration to avoid creating resistant strains.

Side effects

Diarrhea, abdominal pain, vomiting, nausea, flatulence, bad appetite, dry mouth, headache, dizziness, restlessness, insomnia, fatigue, erythema, urticaria, fever, severe diarrhea, pseudomembranous colitis, anaphylaxis, angioedema, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis; thrombocytopenia, leukocytosis, transient eosinophilia; decreased concentration of Hb and hematocrit, hepatitis, jaundice, acute renal failure.

Rare: Prolonged prothrombin time, convulsions.

Drug interactions

Probenecid, warfarin , carbamazepine, nifedipin.

Presentation and packaging

Capsules: 100 mg x 1 blister x 10 tablets; 10 blisters x 10 tablets; 200 mg x 1 blister x 10 tablets; 2 blisters x 10 tablets; 10 blisters x 10 tablets.

Dispersion tablets: 100 mg x 1 blister x 10 tablets; 200 mg x 1 blister x 10 tablets.

Powder for oral suspension: 100 mg x box of 10 sachets x 2 g; 12 sachets x 2 g.

Manufacturers

Domesco.